2023 Prime Minister’s Prize for Innovation

Professor Glenn King

The University of Queensland’s Professor Glenn King received the 2023 Prime Minister’s Prize for Innovation. 

Professor King was recognised for pioneering using peptides from Australian funnel-web spider venom for sustainable crop protection and potentially human therapeutics. 

He first founded the company, Vestaron, which develops safe and eco-friendly insecticides for farmers. This instigated a revolution in crop protection, helping address global food challenges.

He is now the Chief Scientific Officer for Infensa Bioscience, which is developing spider venom therapeutics to help treat strokes and heart attacks. Infensa plans to start Australian-based clinical trials for heart-related therapeutics in 2024. 

Glenn’s research is having impacts in Australia and abroad. Vestaron sells its insecticide products globally, while Infensa continues to create jobs and research opportunities for a new generation of scientists in Australia.

Watch video highlights

Transcript

[Music plays and an image appears of a Prime Minister’s Prize for Innovation medallion above text: Professor Glenn King, PhD, FAAM]

[Image changes to show Prof Glenn King talking to the camera]

Prof Glenn King: As scientists what we’re trying to do is create something of value. 

[Images move through to show a close view of Glenn talking, Glenn working in a lab, a close view of Glenn’s hand holding up a sample of liquid, and Glenn and colleagues in the lab]

Being able to achieve that not once but several times is incredibly rewarding. 

[Images move through to show a medium and then close view of Glenn talking to the camera, and then various views of the Queensland Bioscience Precinct, and text appears: Professor Glenn King]

I’m Professor Glenn King from the Institute for Molecular Bioscience at the University of Queensland and Chief Scientific Officer of Infensa Bioscience. 

[Images move through to show a medium and then close view of Glenn talking to the camera, and then a facing and rear view of Glenn walking around the Queensland Bioscience Precinct]

Early on in my career I got interested in how we could protect crops in an environmentally sustainable way. 

[Images move through to show Glenn talking to the camera, Glenn and a colleague looking at a spider specimen, various insects in test tubes, and a close view of a spider in a plastic container]

So, in the mid-1990s we began to think about ways to protect crops from insect pests and we decided why not turn to the best insect killers on the planet, spiders. 

[Image changes to show Glenn talking to the camera, and then the image changes to show Glenn working in the lab syringing up some pink liquid from a bottle]

What we were searching for were molecules that would kill insects but were completely harmless to humans. 

[Image changes to show Glenn talking to the camera, and then the image changes to show Glenn working in the lab again]

Believe it or not the answer was right here in our backyard. The best molecules were in the venom of the Australian funnel web spider. 

[Images move through to show a close view of Glenn mixing a sample in a tube, and then the image changes to show Glenn talking, and then the image changes to show Glenn with a colleague]

In 2005 I founded a company called Vestaron to try and commercialise these discoveries. 

[Images move through to show Glenn watching a scorpion climb up his colleague’s arm, Glenn talking to the camera, and a close view of the scorpion on a sleeve]

This Australian innovation is now having global impact with these insecticides around the world. 

[Images move through to show Glenn talking to the camera, a close view of Glenn talking, and then a close view of the Infensa Bioscience badge on a uniform shirt]

Ten years of working on spider venom made us realise that the venoms had molecules for human therapeutics and that in turn led to the founding of Infensa Bioscience. 

[Images move through to show test tubes in a tray, test tubes being gently vibrated on a machine, a robotic machine with nozzles, and Glenn and a colleague looking at rows of samples]

30% of all deaths every year are due to stroke or heart attack and yet we do not have a single drug to protect the brain or the heart. 

[Images move through to show Glenn and a colleague talking, Glenn talking to the camera, rows of sample tubes, notations in a book, Glenn talking with his colleague, and Glenn talking to the camera]

Remarkably in the venom of an Australian funnel web spider we found a molecule that protects the brain after stroke, the heart after a heart attack, and helps us maintain the integrity of donor hearts for heart transplant. 

[Images move through to show a spider being transferred from one container to another, Glenn talking to the camera, and the spider under a plastic container on a lab bench]

Infensa plans to start clinical trials for heart attack next year and those clinical trials will be run in Australia. 

[Images move through to show a spider being worked with, Glenn talking to the camera, a close view of a spider being moved into another container, and Glenn and a colleague looking at a spider]

Infensa is truly an Australian story, it’s an Australian innovation, it’s funded by Australians, it’s based in Australia, it’s employing Australians, the benefits will feed back into the Australian economy.

[Images move through to show Glenn talking, a close view of Glenn talking to the camera, Glenn’s colleague looking at a scorpion on her lab coat sleeve, and Glenn smiling while standing in the lab]

I’m incredibly humbled and honoured to have received the Prime Minister’s Prize for Innovation. I hope this will inspire others to push boundaries. 

[Image changes to show a close view of Glenn smiling at the camera]

Don’t forget you’re the innovator, so follow your passion.

[Music plays and the image changes to show a Prime Minister’s Prize for Innovation medallion on the left, the Australian Government Coat of Arms at the bottom right, and text: 2023 Prime Minister’s Prize for Innovation]